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Verorab
Add to WishlistRabies Vaccine BP ≥ 2.5 IU/ml
Powder and......
Rabies Vaccine BP ≥ 2.5 IU/ml
Powder and solvent for suspension for injection.
1. WHAT RABIES VACCINE BP IS AND WHAT IT IS USED FOR
Rabies Vaccine BP is one of a general group of medicines called vaccines. Vaccines are used to protect against infectious diseases. This vaccine helps to protect adults and children against rabies. Rabies Vaccine BP can be used in two ways:
- Vaccinating you before you come into contact with rabies virus.
- Vaccinating you after you have come into contact with rabies virus.
Rabies Vaccine BP is a preparation containing very small amounts of a modified form of the virus that causes rabies. When an injection of Rabies Vaccine BP is given, the body's natural defences will produce protection against rabies.
2. BEFORE YOU ARE GIVEN RABIES VACCINE BP
To make sure that this vaccine is suitable for you or your child, it is important to tell the doctor, nurse or pharmacist if any points below apply. If there is anything you do not understand, ask your doctor, nurse or pharmacist to explain.
Do not have Rabies Vaccine BP if you or your child is:
- allergic (hypersensitive) to Rabies Vaccine BP or any of its ingredients (see section 6).
- allergic (hypersensitive) to neomycin or betapropiolactone because these are used during vaccine production and may be present in the vaccine in small amounts.
- ill, with a high temperature or acute infection, the vaccination will be postponed until you or your child have recovered.
Your doctor or nurse may still decide to give the vaccine even if any of the above points apply to you or your child. This is because rabies is a serious disease.
Take special care with Rabies Vaccine BP
Tell your doctor or nurse if you or your child:
- has a history of allergy (such as hayfever or asthma) as there may be an increased risk of side effects.
- has had any other reactions to the vaccine when given before. Your doctor will decide whether to continue the course and may decide to do a blood test to see if you or your child are protected.
- has any blood disorders such as haemophilia or thrombocytopenia (a condition where you bruise or bleed easily) because you or your child may get bleeding at the injection site.
- is under 1 year old.
Your doctor or nurse will decide if you or your child should receive the vaccine.
Receiving other vaccines or medicines
Steroids and other medicines that can suppress the immune system can make the vaccine less effective. The doctor may want to test you or your child’s blood 2 to 4 weeks afer receiving the vaccine to check that it is working properly.
Please tell your doctor, nurse or pharmacist if you or your child are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Pregnancy and breast-feeding
If you are pregnant, think you may be pregnant or breast-feeding tell the doctor or nurse.
There is no evidence that this vaccine affects the unborn baby or the outcome of pregnancy. The doctor or nurse will be able to decide if you should receive the vaccine.
If you have been in contact with rabies, the doctor or nurse will usually decide to give you the vaccine because rabies is a serious disease.
If you have a high risk of coming into contact with rabies in the near future, the doctor or nurse may decide to give you a course of Rabies Vaccine BP to prevent infection.
Ask your doctor, nurse or pharmacist for advice before taking any medicine.
3. HOW RABIES VACCINE BP IS GIVEN
The vaccination will be given by a doctor or nurse. This is because they are trained in the use of vaccines and are equipped to deal with any uncommon severe allergic reaction to the injection.
Dosage
The dose of vaccine that is required depends on whether or not:
- you or your child has previously received the vaccine
- you or your child has come into contact with a rabid or possibly rabid animal
A) Dose before coming into contact with rabies (precautionary / pre exposure):
A total of three injections (1 millilitre each) of the vaccine will be given; one injection on 3 different days.
| Injections | Time of injection | Day |
| First | When you have your first injection | 0 |
| Second | 7 days after your first injection | 7 |
| Third | 28 days after your first injection | 28 |
The earliest day that the 3rd dose may be given to be effective is day 21.
If you are at regular or continuing risk of exposure to rabies, a booster injection is required one year after the
primary course of 3 injections. Further injections should be given at 3 to 5 year intervals thereafter. If you are
a traveller at intermittent risk of exposure to rabies, your doctor or nurse will assess the need for further
booster injections in line with official guidance.
B) Dose if you or your child has had the three injections above, and you or your child has been in contact with a rabid or possible rabid animal:
A total of two injections (1 millilitre each) of the vaccine will be given; one injection on 2 different days.
| Injections | Time of injection | Day |
| First | As soon as possible | 0 |
| Second | 3 days later | 3 |
Your doctor or nurse will make sure that any bite wounds or scratches are properly cleaned before administering the vaccine.
C) Dose if you or your child are not protected against rabies (have never received rabies vaccine or have not received a full primary course of 3 injections), or if your/your child’s history of immunisation is unknown, and you or your child have been in contact with a rabid or possible rabid animal:
A total of five injections (1 millilitre each) of the vaccine will be given; one injection on 5 different days.
| Injections | Time of injection | Day(s) |
| First | As soon as possible | 0 |
| Second | 3 days after your first injection | 3 |
| Third | 7 days after your first injection | 7 |
| Fourth | 14 days after your first injection | 14 |
| Fifth | 30 (or 28) days after your first injection | 30 (or 28) |
Your doctor or nurse will make sure that any bite wounds or scratches are properly cleaned before administering the vaccine.
In addition to the 5 injections of Rabies Vaccine BP, your doctor or nurse may also give you or your child an injection of Rabies Immunoglobulin with the first vaccine injection. This substance helps to fight rabies infection immediately, while the injections of the vaccine are starting to work. The decision to give you/your child Rabies Immunoglobulin will be based on official guidance.
How the vaccine is administered
The doctor or nurse will make up and shake the vaccine just before it is given, and will check that the liquid is a pinkish colour and that there are no unexpected particles in it. The vaccine is given as an injection into a muscle in the upper part of the arm. The vaccine should not be given into the buttock. If Rabies Immunoglobulin is also being given, then it will be injected at a different site to the vaccination site.
4. POSSIBLE SIDE EFFECTS
Like all medicines and vaccines, Rabies Vaccine BP can cause side effects, although not everybody gets them.
Severe allergic reaction (anaphylaxis)
The signs of a severe allergic reaction include:
- difficulty in breathing, blue discolouration of the tongue or lips
- dizziness (low blood presure) and collapse
- difficulty in swallowing, swelling of the face, lips, tongue and/or throat
If these signs or symptoms occur, they usually develop very quickly after the injection is given and while you are still at the clinic or doctor’s surgery.
If any of these symptoms occur after leaving the place where the injection was given, consult a doctor or go to the emergency department of your nearest hospital IMMEDIATELY.
Serum sickness type reaction
• skin rashes, fever, joint pains and enlarged glands
When these symptoms occur, they usually develop 2-4 weeks after receiving the vaccine
If these symptoms occur, consult a doctor as soon as possible.
These types of allergic reaction are more common in patients receiving a booster dose than in patients receiving their first injections.
Other serious side effects
• inflammation of the brain
• fits (convulsion)
• pain or loss of feeling caused by damage to a nerve (neuropathy)
• numbness and weakness of the legs and arms (including an illness called Guillain-Barré
Syndrome)
• partial loss of movement, or impaired movement (paresis)
Other Side effects
Very common side effects (reported in more than 1 in 10 people) are:
• pain, redness, swelling/hardness and itching at the site of the injection
• headache
• muscle and/or joint pain
• feeling sick
• diarrhoea
• generally feeling unwell
• chills (shivering)
• swollen glands
Common side effects (reported in less than 1 in 10 people but more than 1 in 100) are:
• dizziness
• stomach pain, being sick (vomiting)
• a high temperature (fever)
• itchy skin, rash - the skin may be raised in patches or wheals may appear.
• difficulty in breathing and wheezing
• bruising at the site of the injection
This medicine is Prescription Only Medicine (POM ) and required under medical supervision.
ဤဆေးသည် POM ဆေးအုပ်စုတွင်ပါဝင်သောကြောင့် ဆရာဝန်ညွှန်ကြားချက်အတိုင်းသာ သုံးစွဲသင့်ပါသည်။
Description
Verorab
Rabies Vaccine BP ≥ 2.5 IU/ml
Powder and solvent for suspension for injection.
1. WHAT RABIES VACCINE BP IS AND WHAT IT IS USED FOR
Rabies Vaccine BP is one of a general group of medicines called vaccines. Vaccines are used to protect against infectious diseases. This vaccine helps to protect adults and children against rabies. Rabies Vaccine BP can be used in two ways:
- Vaccinating you before you come into contact with rabies virus.
- Vaccinating you after you have come into contact with rabies virus.
Rabies Vaccine BP is a preparation containing very small amounts of a modified form of the virus that causes rabies. When an injection of Rabies Vaccine BP is given, the body's natural defences will produce protection against rabies.
2. BEFORE YOU ARE GIVEN RABIES VACCINE BP
To make sure that this vaccine is suitable for you or your child, it is important to tell the doctor, nurse or pharmacist if any points below apply. If there is anything you do not understand, ask your doctor, nurse or pharmacist to explain.
Do not have Rabies Vaccine BP if you or your child is:
- allergic (hypersensitive) to Rabies Vaccine BP or any of its ingredients (see section 6).
- allergic (hypersensitive) to neomycin or betapropiolactone because these are used during vaccine production and may be present in the vaccine in small amounts.
- ill, with a high temperature or acute infection, the vaccination will be postponed until you or your child have recovered.
Your doctor or nurse may still decide to give the vaccine even if any of the above points apply to you or your child. This is because rabies is a serious disease.
Take special care with Rabies Vaccine BP
Tell your doctor or nurse if you or your child:
- has a history of allergy (such as hayfever or asthma) as there may be an increased risk of side effects.
- has had any other reactions to the vaccine when given before. Your doctor will decide whether to continue the course and may decide to do a blood test to see if you or your child are protected.
- has any blood disorders such as haemophilia or thrombocytopenia (a condition where you bruise or bleed easily) because you or your child may get bleeding at the injection site.
- is under 1 year old.
Your doctor or nurse will decide if you or your child should receive the vaccine.
Receiving other vaccines or medicines
Steroids and other medicines that can suppress the immune system can make the vaccine less effective. The doctor may want to test you or your child’s blood 2 to 4 weeks afer receiving the vaccine to check that it is working properly.
Please tell your doctor, nurse or pharmacist if you or your child are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Pregnancy and breast-feeding
If you are pregnant, think you may be pregnant or breast-feeding tell the doctor or nurse.
There is no evidence that this vaccine affects the unborn baby or the outcome of pregnancy. The doctor or nurse will be able to decide if you should receive the vaccine.
If you have been in contact with rabies, the doctor or nurse will usually decide to give you the vaccine because rabies is a serious disease.
If you have a high risk of coming into contact with rabies in the near future, the doctor or nurse may decide to give you a course of Rabies Vaccine BP to prevent infection.
Ask your doctor, nurse or pharmacist for advice before taking any medicine.
3. HOW RABIES VACCINE BP IS GIVEN
The vaccination will be given by a doctor or nurse. This is because they are trained in the use of vaccines and are equipped to deal with any uncommon severe allergic reaction to the injection.
Dosage
The dose of vaccine that is required depends on whether or not:
- you or your child has previously received the vaccine
- you or your child has come into contact with a rabid or possibly rabid animal
A) Dose before coming into contact with rabies (precautionary / pre exposure):
A total of three injections (1 millilitre each) of the vaccine will be given; one injection on 3 different days.
| Injections | Time of injection | Day |
| First | When you have your first injection | 0 |
| Second | 7 days after your first injection | 7 |
| Third | 28 days after your first injection | 28 |
The earliest day that the 3rd dose may be given to be effective is day 21.
If you are at regular or continuing risk of exposure to rabies, a booster injection is required one year after the
primary course of 3 injections. Further injections should be given at 3 to 5 year intervals thereafter. If you are
a traveller at intermittent risk of exposure to rabies, your doctor or nurse will assess the need for further
booster injections in line with official guidance.
B) Dose if you or your child has had the three injections above, and you or your child has been in contact with a rabid or possible rabid animal:
A total of two injections (1 millilitre each) of the vaccine will be given; one injection on 2 different days.
| Injections | Time of injection | Day |
| First | As soon as possible | 0 |
| Second | 3 days later | 3 |
Your doctor or nurse will make sure that any bite wounds or scratches are properly cleaned before administering the vaccine.
C) Dose if you or your child are not protected against rabies (have never received rabies vaccine or have not received a full primary course of 3 injections), or if your/your child’s history of immunisation is unknown, and you or your child have been in contact with a rabid or possible rabid animal:
A total of five injections (1 millilitre each) of the vaccine will be given; one injection on 5 different days.
| Injections | Time of injection | Day(s) |
| First | As soon as possible | 0 |
| Second | 3 days after your first injection | 3 |
| Third | 7 days after your first injection | 7 |
| Fourth | 14 days after your first injection | 14 |
| Fifth | 30 (or 28) days after your first injection | 30 (or 28) |
Your doctor or nurse will make sure that any bite wounds or scratches are properly cleaned before administering the vaccine.
In addition to the 5 injections of Rabies Vaccine BP, your doctor or nurse may also give you or your child an injection of Rabies Immunoglobulin with the first vaccine injection. This substance helps to fight rabies infection immediately, while the injections of the vaccine are starting to work. The decision to give you/your child Rabies Immunoglobulin will be based on official guidance.
How the vaccine is administered
The doctor or nurse will make up and shake the vaccine just before it is given, and will check that the liquid is a pinkish colour and that there are no unexpected particles in it. The vaccine is given as an injection into a muscle in the upper part of the arm. The vaccine should not be given into the buttock. If Rabies Immunoglobulin is also being given, then it will be injected at a different site to the vaccination site.
4. POSSIBLE SIDE EFFECTS
Like all medicines and vaccines, Rabies Vaccine BP can cause side effects, although not everybody gets them.
Severe allergic reaction (anaphylaxis)
The signs of a severe allergic reaction include:
- difficulty in breathing, blue discolouration of the tongue or lips
- dizziness (low blood presure) and collapse
- difficulty in swallowing, swelling of the face, lips, tongue and/or throat
If these signs or symptoms occur, they usually develop very quickly after the injection is given and while you are still at the clinic or doctor’s surgery.
If any of these symptoms occur after leaving the place where the injection was given, consult a doctor or go to the emergency department of your nearest hospital IMMEDIATELY.
Serum sickness type reaction
• skin rashes, fever, joint pains and enlarged glands
When these symptoms occur, they usually develop 2-4 weeks after receiving the vaccine
If these symptoms occur, consult a doctor as soon as possible.
These types of allergic reaction are more common in patients receiving a booster dose than in patients receiving their first injections.
Other serious side effects
• inflammation of the brain
• fits (convulsion)
• pain or loss of feeling caused by damage to a nerve (neuropathy)
• numbness and weakness of the legs and arms (including an illness called Guillain-Barré
Syndrome)
• partial loss of movement, or impaired movement (paresis)
Other Side effects
Very common side effects (reported in more than 1 in 10 people) are:
• pain, redness, swelling/hardness and itching at the site of the injection
• headache
• muscle and/or joint pain
• feeling sick
• diarrhoea
• generally feeling unwell
• chills (shivering)
• swollen glands
Common side effects (reported in less than 1 in 10 people but more than 1 in 100) are:
• dizziness
• stomach pain, being sick (vomiting)
• a high temperature (fever)
• itchy skin, rash - the skin may be raised in patches or wheals may appear.
• difficulty in breathing and wheezing
• bruising at the site of the injection
This medicine is Prescription Only Medicine (POM ) and required under medical supervision.
ဤဆေးသည် POM ဆေးအုပ်စုတွင်ပါဝင်သောကြောင့် ဆရာဝန်ညွှန်ကြားချက်အတိုင်းသာ သုံးစွဲသင့်ပါသည်။
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