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Carvid 6.25

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SKU: B00740238
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1. CARVID 6.25 (Carvediol 6.25 mg Tablets)
E......

1. CARVID 6.25 (Carvediol 6.25 mg Tablets)
Each uncoated tablet contains:
Carvedilol BP                      6.25mg
Excipients                            q.s.


2. INDICATIONS
    Hypertension
    Angina Pectoris
    Adjunct to diuretics, digoxin, or ACE inhibitors in symptomatic chronic heart failure.


3. CONTRAINDICATIONS
Carvid is contra-indicated in patients with marked fluid retention or overload requiring intravenous inotropic support. Patients with obstructive airways disease, liver dysfunction, hypersensitivity to carvedilol or any other constituents of the tablets. As with other beta-blocking agents: History of bronchospasm or asthma, 2nd and 3rd degree A-V heart block, uncontrolled heart failure, Prinzmetal’s angina, severe bradycardia (<50bpm), cardiogenic shock, sick sinus syndrome (including sinoatrial block), severe hypotension (systolic blood pressure < 85mmHg), metabolic acidosis and phaeochromocytoma (unless adequately controlled by alpha blockade).


4. UNDERSIRABLE EFFECTS
The following side-effects may occur:
Cardiovascular, Postural hypotension and bradycardia can occur.
Exacerbation of peripheral vascular disease, development of Raynaud’s phenomenon (due to unopposed arteriolar alpha-sympathetic activation), and even peripheral gangrene may be precipitated.
Congestive cardiac failure can be precipiated or worsened, especially during dose titration. Heart block may be precipitated in patients with underlying cardiac disorders. Chest pain, generalized oedema and syncope have also been reported.
Respiratory: Bronchoconstriction, wheeze and dyspnoea may occur in patients with asthma, bronchitis and other chronic pulmonary diseases.
Gastro-intestinal and hepatobiliary: Diarrhoea, nausea , vomiting, constipation, abdominal cramps and hepatic injury (elevated transaminases) have been reported.
General: Vague fatigue and malaise, which is usually mild and occurs particularly after initiation of therapy. Stuffy nose, fever and weight gain occurs rarely.
Urogenital: Sexual impotence, reduced libido, hematuria, urine retention and deterioration of renal function in patients with CHF.
Musculoskeletal: Muscle weakness, muscle cramps, myopathies and cold extremities.
Neuropsychiatric: This may range from vague fatigue and malaise, isomnia, vivid dreams and nightmares, to overt psychosis. Paresthesia( including tingling of the scalp) and peripheral neuropathy have also been reported.
Haematological: Non-thrombocytopenic purpura, thrombocytopenia, agranulocytosis, transient eosinophilia and leucopenia.
Dermatological: Allergic skin reactions, reversible alopecia, stomatitis and angioedema. Psoriasis may be aggravated or induced by carvedilol.


5. DOSAGE & ADMINISTRATION
In hypertension, initial oral dose of 12.5 mg once daily. Increased after 2 days to usual dose of 25mg once daily,if necessary may be further increased at interval of atleast 2 weeks to maximum 50 mg daily in single or divided doses. Elderly initial dose of 12.5 mg daily may provide satisfactory control. In angina pectoris an initial oral dose of 12.5 mg is given twice daily, increased after two days to 25mg twice daily. Adjunct in heart failure initially 3.125 mg   twice daily (with food), dose increased at intervals of at least 2 weeks of 6.25 mg twice daily; increase to highest dose tolerated, max. 25mg twice daily in patients with severe heart failure or body weight less than 85 kg and 52 mg twice daily in patients over 85 kg.


This medicine is Prescription Only Medicine (POM ) and required under medical supervision.

ဤဆေးသည် POM ဆေးအုပ်စုတွင်ပါဝင်သောကြောင့် ဆရာဝန်ညွှန်ကြားချက်အတိုင်းသာ သုံးစွဲသင့်ပါသည်။

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Size : 3x10's = 30 tablets

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1 × 3,450 Ks

[ 1 × 3,450 Ks ]

Description

Carvid 6.25

1. CARVID 6.25 (Carvediol 6.25 mg Tablets)
Each uncoated tablet contains:
Carvedilol BP                      6.25mg
Excipients                            q.s.


2. INDICATIONS
    Hypertension
    Angina Pectoris
    Adjunct to diuretics, digoxin, or ACE inhibitors in symptomatic chronic heart failure.


3. CONTRAINDICATIONS
Carvid is contra-indicated in patients with marked fluid retention or overload requiring intravenous inotropic support. Patients with obstructive airways disease, liver dysfunction, hypersensitivity to carvedilol or any other constituents of the tablets. As with other beta-blocking agents: History of bronchospasm or asthma, 2nd and 3rd degree A-V heart block, uncontrolled heart failure, Prinzmetal’s angina, severe bradycardia (<50bpm), cardiogenic shock, sick sinus syndrome (including sinoatrial block), severe hypotension (systolic blood pressure < 85mmHg), metabolic acidosis and phaeochromocytoma (unless adequately controlled by alpha blockade).


4. UNDERSIRABLE EFFECTS
The following side-effects may occur:
Cardiovascular, Postural hypotension and bradycardia can occur.
Exacerbation of peripheral vascular disease, development of Raynaud’s phenomenon (due to unopposed arteriolar alpha-sympathetic activation), and even peripheral gangrene may be precipitated.
Congestive cardiac failure can be precipiated or worsened, especially during dose titration. Heart block may be precipitated in patients with underlying cardiac disorders. Chest pain, generalized oedema and syncope have also been reported.
Respiratory: Bronchoconstriction, wheeze and dyspnoea may occur in patients with asthma, bronchitis and other chronic pulmonary diseases.
Gastro-intestinal and hepatobiliary: Diarrhoea, nausea , vomiting, constipation, abdominal cramps and hepatic injury (elevated transaminases) have been reported.
General: Vague fatigue and malaise, which is usually mild and occurs particularly after initiation of therapy. Stuffy nose, fever and weight gain occurs rarely.
Urogenital: Sexual impotence, reduced libido, hematuria, urine retention and deterioration of renal function in patients with CHF.
Musculoskeletal: Muscle weakness, muscle cramps, myopathies and cold extremities.
Neuropsychiatric: This may range from vague fatigue and malaise, isomnia, vivid dreams and nightmares, to overt psychosis. Paresthesia( including tingling of the scalp) and peripheral neuropathy have also been reported.
Haematological: Non-thrombocytopenic purpura, thrombocytopenia, agranulocytosis, transient eosinophilia and leucopenia.
Dermatological: Allergic skin reactions, reversible alopecia, stomatitis and angioedema. Psoriasis may be aggravated or induced by carvedilol.


5. DOSAGE & ADMINISTRATION
In hypertension, initial oral dose of 12.5 mg once daily. Increased after 2 days to usual dose of 25mg once daily,if necessary may be further increased at interval of atleast 2 weeks to maximum 50 mg daily in single or divided doses. Elderly initial dose of 12.5 mg daily may provide satisfactory control. In angina pectoris an initial oral dose of 12.5 mg is given twice daily, increased after two days to 25mg twice daily. Adjunct in heart failure initially 3.125 mg   twice daily (with food), dose increased at intervals of at least 2 weeks of 6.25 mg twice daily; increase to highest dose tolerated, max. 25mg twice daily in patients with severe heart failure or body weight less than 85 kg and 52 mg twice daily in patients over 85 kg.


This medicine is Prescription Only Medicine (POM ) and required under medical supervision.

ဤဆေးသည် POM ဆေးအုပ်စုတွင်ပါဝင်သောကြောင့် ဆရာဝန်ညွှန်ကြားချက်အတိုင်းသာ သုံးစွဲသင့်ပါသည်။

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